Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.9/2415
Título: Biomarkers of exposure to metal dust in exhaled breath condensate: methodology optimization
Autor: Félix, P. M.
Franco, C.
Barreiros, Maria Alexandra
Batista, B.
Bernardes, S.
Garcia, S. M.
Almeida, A. B.
Almeida, S. M.
Wolterbeek, H. Th.
Pinheiro, Teresa
Palavras-chave: Metal exposure
Data: 2013
Editora: Taylor & Francis
Citação: Félix, P.M.; Franco, C.; Barreiros, .A.; Batista, B.; Bernardes, S.; Garcia, S.M.; Almeida, A.B.; Almeida, S.M.; Wolterbeek, H. Th.; Pinheiro, T. Biomarkers of exposure to metal dust in exhaled breath condensate: methodology optimization. In: Archives of Environmental & Occupational Health, 2013, Vol. 68, nº 2, p. 72-79
Resumo: In occupational assessments where workers are exposed to metal dust, the liquid condensate of exhaled breath (EBC) may provide unique indication of pulmonary exposure. The main goal of this study was to demonstrate the quality of EBC to biological monitoring of human exposure. A pilot study was performed in a group of metal dust–exposed workers and a group of nonexposed individuals working in offices. Only metal dust–exposed workers were followed along the working week to determine the best time of collection. Metal analyses were performed with inductively coupled plasma mass spectrometry (ICP-MS). Analytical methodology was tested using an EBC sample pool for several occupationally exposed metals: potassium, chromium, manganese, copper, zinc, strontium, cadmium, antimony, and lead. Metal contents in EBC of exposed workers were higher than controls at the beginning of the shift and remained augmented throughout the working week. The results obtained support the establishment of EBC as an indicator of pulmonary exposure to metals.
URI: http://hdl.handle.net/10400.9/2415
ISSN: 1933-8244
Versão do Editor: http://dx.doi.org/10.1080/19338244.2011.638951
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