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Biomarkers of exposure to metal dust in exhaled breath condensate: methodology optimization

2013Journal article Open access
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dc.contributor.authorFélix, P. M.
dc.contributor.authorFranco, C.
dc.contributor.authorBarreiros, M. Alexandra
dc.contributor.authorBatista, B.
dc.contributor.authorBernardes, S.
dc.contributor.authorGarcia, S. M.
dc.contributor.authorAlmeida, A. B.
dc.contributor.authorAlmeida, S. M.
dc.contributor.authorWolterbeek, H. Th.
dc.contributor.authorPinheiro, Teresa
dc.date.accessioned2014-04-15T16:13:50Z
dc.date.available2014-04-15T16:13:50Z
dc.date.issued2013
dc.description.abstractIn occupational assessments where workers are exposed to metal dust, the liquid condensate of exhaled breath (EBC) may provide unique indication of pulmonary exposure. The main goal of this study was to demonstrate the quality of EBC to biological monitoring of human exposure. A pilot study was performed in a group of metal dust–exposed workers and a group of nonexposed individuals working in offices. Only metal dust–exposed workers were followed along the working week to determine the best time of collection. Metal analyses were performed with inductively coupled plasma mass spectrometry (ICP-MS). Analytical methodology was tested using an EBC sample pool for several occupationally exposed metals: potassium, chromium, manganese, copper, zinc, strontium, cadmium, antimony, and lead. Metal contents in EBC of exposed workers were higher than controls at the beginning of the shift and remained augmented throughout the working week. The results obtained support the establishment of EBC as an indicator of pulmonary exposure to metals.por
dc.identifier.citationFélix, P.M.; Franco, C.; Barreiros, .A.; Batista, B.; Bernardes, S.; Garcia, S.M.; Almeida, A.B.; Almeida, S.M.; Wolterbeek, H. Th.; Pinheiro, T. Biomarkers of exposure to metal dust in exhaled breath condensate: methodology optimization. In: Archives of Environmental & Occupational Health, 2013, Vol. 68, nº 2, p. 72-79por
dc.identifier.issn1933-8244
dc.identifier.urihttp://hdl.handle.net/10400.9/2415
dc.language.isoengpor
dc.publisherTaylor & Francispor
dc.relation.publisherversionhttp://dx.doi.org/10.1080/19338244.2011.638951por
dc.subjectMetal exposurepor
dc.subjectBiomonitoringpor
dc.subjectICP-MSpor
dc.subjectLeadpor
dc.subjectTXRFpor
dc.titleBiomarkers of exposure to metal dust in exhaled breath condensate: methodology optimizationpor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage79por
oaire.citation.startPage72por
oaire.citation.titleArchives of Environmental & Occupational Healthpor
oaire.citation.volume68por
person.familyNameBarreiros
person.givenNameMaria Alexandra
person.identifierL-4674-2014
person.identifier.ciencia-id271D-7B29-E46C
person.identifier.orcid0000-0002-0132-4969
person.identifier.scopus-author-id6603680496
rcaap.rightsopenAccesspor
rcaap.typearticlepor
relation.isAuthorOfPublication3b1e7d6a-3232-443e-a747-f442427dc57a
relation.isAuthorOfPublication.latestForDiscovery3b1e7d6a-3232-443e-a747-f442427dc57a

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