Publication
Novel 1-hydroxy-1,1-bisphosphonates derived from indazole: synthesis and characterization
| dc.contributor.author | Teixeira, Fatima | |
| dc.contributor.author | Antunes, Inês F. | |
| dc.contributor.author | Curto, Maria João Marcelo | |
| dc.contributor.author | Neves, M. | |
| dc.contributor.author | Teixeira, António P. S. | |
| dc.date.accessioned | 2010-06-23T15:06:26Z | |
| dc.date.available | 2010-06-23T15:06:26Z | |
| dc.date.issued | 2009 | |
| dc.description.abstract | Bisphosphonates (BPs) are an important class of drugs used in the treatment of abnormal calcium metabolism diseases. The first syntheses of bisphosphonates derived from indazole, substituted at the N-1, N-2 and C-3 positions are reported. The 1-hydroxy-1,1-bisphosphonates were synthesized from the corresponding carboxylic acid or acyl chloride compounds, by two different methods. These BPs have a side chain with different lengths ((CH2)n, n = 0-5) between the indazole ring and the bisphosphonate group. | pt |
| dc.identifier.citation | Teixeira, Fátima C.; Antunes, Inês F.; Curto, Maria J. Marcelo; Neves, M; Teixeira, António P. S. Novel 1-hydroxy-1,1-bisphosphonates derived from indazole: synthesis and characterization. In: Arkivoc,vol XI, 2009, p.69-84 | pt |
| dc.identifier.uri | http://hdl.handle.net/10400.9/703 | |
| dc.language.iso | eng | pt |
| dc.subject | Bisphosphonates | pt |
| dc.subject | Indazole | pt |
| dc.subject | N-1 and N-2 isomers | pt |
| dc.subject | Spectroscopic characterization | pt |
| dc.title | Novel 1-hydroxy-1,1-bisphosphonates derived from indazole: synthesis and characterization | pt |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 84 | pt |
| oaire.citation.startPage | 69 | pt |
| oaire.citation.title | Arkivoc | pt |
| person.familyName | Teixeira | |
| person.familyName | Teixeira | |
| person.givenName | Fatima | |
| person.givenName | António Paulo Silva | |
| person.identifier.ciencia-id | C014-509B-D1DC | |
| person.identifier.orcid | 0000-0003-0801-2068 | |
| person.identifier.orcid | 0000-0001-7448-0893 | |
| person.identifier.rid | N-5456-2014 | |
| person.identifier.scopus-author-id | 7102746385 | |
| person.identifier.scopus-author-id | 36856362300 | |
| rcaap.rights | openAccess | pt |
| rcaap.type | article | pt |
| relation.isAuthorOfPublication | 3daa40f1-7bb6-488d-83d9-04a61c655d67 | |
| relation.isAuthorOfPublication | d8ff15d1-5d27-4e57-8654-f0f85fd79510 | |
| relation.isAuthorOfPublication.latestForDiscovery | 3daa40f1-7bb6-488d-83d9-04a61c655d67 |