Publication
Saccharomycin, a biocide from S. cerevisiae that kill-off other yeasts
| dc.contributor.author | Caldeira, Jorge | |
| dc.contributor.author | Gabriela Almeida, M. | |
| dc.contributor.author | Macedo, Anjos L. | |
| dc.contributor.author | Silva, José P. M. | |
| dc.contributor.author | Albergaria, Helena | |
| dc.date.accessioned | 2020-04-01T08:47:14Z | |
| dc.date.available | 2020-04-01T08:47:14Z | |
| dc.date.issued | 2019 | |
| dc.description.abstract | ABSTRACT: Introduction: Saccharomyces cerevisiae plays an important role in alcoholic fermentation and is involved in the production of wine, beer and bread. Recent studies [1–7] showed that S. cerevisiae secretes antimicrobial peptides (AMPs), named “saccharomycin”, derived from the glycolytic enzyme glyceraldehyde 3-phosphate dehydrogenase (GAPDH) that are active against a variety of wine-related microbial species. AMPs are low molecular weight proteins with broad antimicrobial spectrum of action against bacteria, viruses, and fungi [8]. Organisms use AMPs for defence against infection and membrane interaction appears to be the key to this antimicrobial function: generally they adopt amphiphilic structures that interact with the infectious agent’s membrane. AMPs constitute a promising source as alternatives to: i) combat pathogenic bacteria resistant to common antibiotics and ii) substitute chemical preservatives in food-fermented products such as wine. The aim of this study was to discover the mode of action of these peptides by detailed chemical structure characterisation and cell contact mechanism. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Caldeira, Jorge... [et.al.] - Saccharomycin, a biocide from S. cerevisiae that kill-off other yeasts. In: Annals of Medicine, 2019, Vol. 51, supplement 1, p. S94-S96 | pt_PT |
| dc.identifier.doi | 10.1080/07853890.2018.1562694 | pt_PT |
| dc.identifier.issn | 0785-3890 | |
| dc.identifier.uri | http://hdl.handle.net/10400.9/3226 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | Taylor & Francis | pt_PT |
| dc.relation | POCI-01-0145-FEDER-007728 | pt_PT |
| dc.relation | BIOPEPTIDES- Biopreservation of Ethanolic Fermentations: antimicrobial activity, biochemical properties and molecular characterization of yeast peptides | |
| dc.relation.publisherversion | https://doi.org/10.1080/07853890.2018.1562694 | pt_PT |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt_PT |
| dc.subject | Saccharomyces cerevisiae | pt_PT |
| dc.subject | Yeasts | pt_PT |
| dc.subject | Alcoholic fermentation | pt_PT |
| dc.title | Saccharomycin, a biocide from S. cerevisiae that kill-off other yeasts | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.awardTitle | BIOPEPTIDES- Biopreservation of Ethanolic Fermentations: antimicrobial activity, biochemical properties and molecular characterization of yeast peptides | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/5876-PPCDTI/PTDC%2FAGR-ALI%2F113565%2F2009/PT | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/5876/UID%2FMulti%2F04378%2F2013/PT | |
| oaire.citation.endPage | 96 | pt_PT |
| oaire.citation.startPage | 94 | pt_PT |
| oaire.citation.title | Annals of Medicine | pt_PT |
| oaire.citation.volume | 51 | pt_PT |
| oaire.fundingStream | 5876-PPCDTI | |
| oaire.fundingStream | 5876 | |
| person.familyName | Almeida | |
| person.familyName | Macedo | |
| person.familyName | Albergaria | |
| person.givenName | Gabriela | |
| person.givenName | Anjos | |
| person.givenName | Helena | |
| person.identifier.ciencia-id | DF16-FBB4-3564 | |
| person.identifier.ciencia-id | FF10-6CD1-AF19 | |
| person.identifier.orcid | 0000-0002-4508-7379 | |
| person.identifier.orcid | 0000-0002-2613-4838 | |
| person.identifier.orcid | 0000-0002-9062-9827 | |
| person.identifier.rid | D-8265-2013 | |
| person.identifier.rid | D-7216-2013 | |
| person.identifier.rid | A-8351-2015 | |
| person.identifier.scopus-author-id | 15768609100 | |
| person.identifier.scopus-author-id | 7101906726 | |
| person.identifier.scopus-author-id | 7801441357 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |
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